| DATE | OPPONENT | SCORE | RECORD/BIG 12 |
| Aug 30 | at Tulsa | W 37-0 | 1-0 |
| Sept 7 | Alabama | W 37-27 | 2-0 |
| Sept 14 | Texas-El Paso | W 68-0 | 3-0 |
| Sept 28 | South Florida | W 31-14 | 4-0 |
| Oct 5 | at Missouri* | W 31-24 | 5-0 / 1-0 |
| Oct 12 | Texas (at Dallas)* | W 35-24 | 6-0 / 2-0 |
| Oct 19 | Iowa State* | W 49-3 | 7-0 / 3-0 |
| Nov 2 | Colorado* | W 27-11 | 8-0 / 4-0 |
| Nov 9 | at Texas A&M* | L 30-26 | 8-1 / 4-1 |
| Nov 16 | at Baylor* | W 49-9 | 9-1 / 5-1 |
| Nov 23 | Texas Tech* | W 60-15 | 10-1 / 6-1 |
| Nov 30 | at Oklahoma State* | L 38-28 | 10-2 / 6-2 |
| Dec 7 | Colorado* Houston - Big 12 Championship |
W 29-7 | 11-2 / 7-2 |
| Jan 1 | Washington State Rose Bowl |
W 34-14 | 12-2 / 7-2 |